Nikon Clinical Microscope Review – Model: Eclipse 200 LED

Nikon Eclipse 200 LED Microscope  

Nikon E200


Objectives: Nikon employs it’s CFi60 E Plan objective lenses (pictured below) to achieve excellent resolution and clarity on the E200. The E Plan objectives deliver long working distances, high numerical apertures and flat images over the entire field of view with virtually no curvature of field when used in conjunction with Nikon’s 10x/20mm field of view eyepieces.  The E200 can hold 4 objectives at once and comes standard with a 4x, 10x, 40x E Plan dry brightfield objective set. A 100x oil immersion is also included in the MSRP of $2,049.00 US Dollars. Nikon also offers phase objectives as well as a 2x, 20x, 60x and 50x oil immersion objectives that can be substituted at an additional cost. The 2x and Phase objectives will require a specialized condenser.  


Eyepieces: Nikon’s CFi 10x/22mm eyepieces employ diopters to make both eyepieces adjustable. They can be dialed in for phenomenal sharpness and parfocality, so that no coarse focus adjustment is needed when switching back and forth between the 10x and 40x objective lenses.  Each eyepiece has a built in reticle shelf which can accommodate an ocular micrometer, miller disc, or Howard mold count reticle. Nikon’s quality control team ensures that the same chromium free glass that is used in the objective lenses is used in their adjustable eyepieces. 15x eyepieces are available at an additional cost from an authorized Nikon microscope dealer. 

Condenser: The Nikon E200 comes with a 1.25 brightfield abbe condenser and auxiliary lens. The auxiliary lens allows for full field of view under the 4x objective lens without shadows. The condenser employs a leaf diaphragm which allows the microscopist to accurately set  the condenser to the corresponding objective each time.  The E200 condenser is centered and does not require Koehler illumination. Phase, darkfield (dry and oil immersion), and phase turret condensers are available from Nikon as an upgrade. A swing out condenser for a 2x objective can also be substituted for an additional cost for Pathology and Mohs Dermpathology microscopy.


Stage: Nikon uses a belt driven right handed scratch resistant mechanical stage to achieve optimum range of motion across the x and y axis. The left handed slide release allows for simple specimen switch out for high volume labs. The stage mechanism is equipped with a “push down” reset where the specimen can be changed out without the need to refocus. The wide platform and long fingered specimen holder can accommodate two slides for comparative viewing of specimens. 

Focus System:  Nikon’s coarse and fine focus employ ultra smooth mechanics for ease of use. The focus system comes with a torque ring which can be adjusted to specific user needs and preferences. The focus system also has an upper limit stop which protects slides and specimens. This is especially useful for teaching environments such as the college level biology labs where students are prone to breaking specimen slides which causes glass to get down in the gears and optical path.

Illumination  System 

LED: Nikon has engineered an eco friendly light emitting diode system in conjunction with a “fly eye lens” which illuminates the entire field of view with clean white light. The use of the LED illumination system eliminates the need for a color correcting blue filter found in halogen microscopes of years gone by. This makes for less eye strain on the microscopist.  The LED’s low power consumption and operating temperature extends the life of the electrical components which drive the microscopes light source. The intensity of the light can be varied. The light output is bright enough for a teaching head configuration. 


5 Years: Nikon offers a 5 year warranty on optics, mechanics, and even the electrical system (Most of Nikon’s competitors offer only 1 year on Electrical). This ensures that the microscope is free from manufacturer’s defects. In the event that your Nikon E200 is damaged from user error, microscope parts for the E200 can be purchased online. You may also use Nikon’s database to find an authorized Nikon microscope repair representative in your vicinity for on-site repairs and regularly scheduled preventative microscope maintenance.  

Where to Buy

Online:  The Nikon E200 LED Microscope can be bought online with immediate delivery from an authorized Nikon clinical microscope dealer. Bulk discounts are frequently offered for universities and hospitals.

Target Audience  

Best Fit: Nikon designed the Eclipse 200 LED microscope to fit a wide range of clinical applications. The E200 is modular which means components can always be added at a later date. The strong mechanical design and high quality optics make the E200 a favorite among laboratory managers, veterinarians, and universities. The Nikon E200 is truly a universal microscope which works well across the clinical spectrum. The brochure for the Nikon E200 can be downloaded at the following link: Nikon E200 Brochure

Overall Recommendation

Strong buy. The Nikon E200 is our favorite fixed head microscope for clinical microscopy. The high quality Nikon optics and super smooth mechanics make using the Nikon E200 a pleasure for everyday lab use. We would be hard priced to find a better microscope in the same price range. We prefer the Nikon Eclipse 200 over the Olympus CX series and the Leica DM series.  Nikon’s quality control team ensures that no E200 is sold without meeting Nikon’s renowned quality control standards.

Top 5 Microscope Manufacturers.

1) Nikon

The highest quality optics, durability of mechanical components, and customer service have Nikon ranked as our number one choice. This Japanese based company is second to none in quality control.

2) Olympus

Olympus comes in a strong second as a company known for performance and ergonomics on it’s microscopes. Olympus has a wide variety of accessories and custom options. Their price point is a bit higher than we would like to see, especially when compared to Nikon.

3) Leica

Leica ranks third in our opinion. The once great German optical company seems to have moved manufacturing outside of Europe on some microscopes.  Still, Leica is a strong choice due to their optical quality. Pricing on their oil immersion objectives is one factor keeping them from ranking higher.

4) Meiji

The only microscope company that manufacturers it’s microscopes completely in Japan as of this writing. (Nikon and Olympus, both Japanese companies have opted to manufacture throughout Asia at this point) Meiji is not a well known name, but based on price and quality, they’re definitely in the top 5. They are a leader in stereo microscopes for industrial purposes.

5) Zeiss

Zeiss still makes the world’s best surgery microscopes. However their upright compound microscopes don’t seem to be in the same class that they once were. This quality fall off and the price have Zeiss microscopes down in the 5th position. Customer service is also a challenge.